Voprosy meditsinskoi khimii (ISSN 0042-8809)

Optimization of a method of determination of endogenous ethanol in the blood and tissues of man and experimental animals

   
Shishkin S.N., Ostrovskii Iu.M., Pron'ko P.S.
PubMed Id: 3218128
Year: 1988 vol: 34  issue:5  pages: 129-133
Abstract: An improved procedure is described for estimation of endogenous ethanol in human and animal biological fluids using gas chromatographic analysis of equilibrated steam. Sensitivity of the procedure was as low as 0.05 mg/L and relative error--about 6%. Content of endogenous ethanol constituted from 0.08 mg/L to 1.30 mg/l (the mean value was 0.38 +/- 0.07 mg/L) in blood of healthy men which did not consume alcohol for a long time. In blood and tissues of white rats content of ethanol was equal to 0.06-1.32 mg/L and 0.07-3.12 mg/l, respectively.
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Reference: Shishkin S.N., Ostrovskii Iu.M., Pron'ko P.S., Optimization of a method of determination of endogenous ethanol in the blood and tissues of man and experimental animals, Voprosy meditsinskoi khimii, 1988, vol: 34(5), 129-133.
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