Voprosy meditsinskoi khimii (ISSN 0042-8809)

Low molecular weight and protein dinitrosyl complexes of non-heme iron as inhibitors of platelet aggregation

   
Kuznetsov V.A., Mordvintsev P.I., Dank E.Kh., Iurkiv V.A., Vanin A.F.
PubMed Id: 2851211
Year: 1988 vol: 34  issue:5  pages: 43-46
Abstract: Dinitrosyl complexes of ferrum with thiosulfate or reduced glutathione were found to inhibit completely aggregation of human thrombocytes, suspended in artificial protein-free medium. The inhibitory effect appears to occur as a result of activating action of nitrogen oxide derived from the complexes and affecting the thrombocyte guanylate cyclase.
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Reference: Kuznetsov V.A., Mordvintsev P.I., Dank E.Kh., Iurkiv V.A., Vanin A.F., Low molecular weight and protein dinitrosyl complexes of non-heme iron as inhibitors of platelet aggregation, Voprosy meditsinskoi khimii, 1988, vol: 34(5), 43-46.
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