Voprosy meditsinskoi khimii (ISSN 0042-8809)

The use of a tripeptide chromogenic substrate for simultaneous determination of 4 indices of kallikrein-kinin system

   
Dotsenko V.L., Iarovaia G.A., Neshkova E.A.
PubMed Id: 2741408
Year: 1989 vol: 35  issue:2  pages: 128-133
Abstract: Evaluation of the kallikrein-kinine system activity in blood plasma is of importance due to participation of the components of this system in regulation of blood plasma proteolysis. Using D-Pro-Phe-Arg-pNA as a substrate, a procedure for simultaneous estimation of four patterns of the kallikrein-kinine system activity was developed: I. maintenance of contact phase, 2. content of prekallikrein (1.49 un/ml in normal state), 3. activity of kallikrein (0.104 un/ml), 4. antikallikrein potential (0.700 IU/ml).
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Reference: Dotsenko V.L., Iarovaia G.A., Neshkova E.A., The use of a tripeptide chromogenic substrate for simultaneous determination of 4 indices of kallikrein-kinin system, Voprosy meditsinskoi khimii, 1989, vol: 35(2), 128-133.
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