Voprosy meditsinskoi khimii (ISSN 0042-8809)

Mechanism of changes in amine binding to plasma proteins during allergy

   
Shleikin A.G., Gor'kova L.B., Pozhilenkova K.S., Zvezdochkin A.G.
PubMed Id: 2741420
Year: 1989 vol: 35  issue:2  pages: 86-89
Abstract: Blood plasma of healthy persons bound 13.13 +/- 1.07 mmol/l of p-phenylene diamine (PDA), histamine pectic index constituted 33.3 +/- 2.18%. In patients with neurodermitis and eczema both these patterns were markedly reduced. Unitiol (10(-3) mol/l) increased PDA binding and histamine level in vitro. The same concentration of cystamine decreased histamine pectic index in healthy persons. Importance of protein SH-groups in binding of amines is discussed.
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Reference: Shleikin A.G., Gor'kova L.B., Pozhilenkova K.S., Zvezdochkin A.G., Mechanism of changes in amine binding to plasma proteins during allergy, Voprosy meditsinskoi khimii, 1989, vol: 35(2), 86-89.
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