Voprosy meditsinskoi khimii (ISSN 0042-8809)

Cationic proteins from neutrophils as inhibitors of nonenzymatic fibrinolytic and anticoagulant activity of blood plasma

   
Kudriashov B.A., Liapina L.A., Kokriakov V.N., Azieva L.D., Pigarevskiĭ V.E., Aleshina G.M., Ashmarin I.P.
PubMed Id: 2528237
Year: 1989 vol: 35  issue:3  pages: 103-108
Abstract: Two cation proteins free of enzymatic activity, containing one and four peptides (CP-1 and CP-4, respectively), were studied. The cation protein consisting of four peptides proved to be the most effective inhibitor of the nonenzymatic fibrinolytic activity of heparin-containing complexes. Both these cation proteins inhibited similarly the anticoagulation activity of blood plasma. The drugs, like cation proteins, appear to be potentially important for clinical practice under conditions of excessive hemorrhage caused by elevated level in circulation of complexes containing heparin and proteins.
Download PDF:
Reference: Kudriashov B.A., Liapina L.A., Kokriakov V.N., Azieva L.D., Pigarevskiĭ V.E., Aleshina G.M., Ashmarin I.P., Cationic proteins from neutrophils as inhibitors of nonenzymatic fibrinolytic and anticoagulant activity of blood plasma, Voprosy meditsinskoi khimii, 1989, vol: 35(3), 103-108.
References
 1995(Vol:41)
 1994(Vol:40)
 1993(Vol:39)
 1992(Vol:38)
 1991(Vol:37)
 1990(Vol:36)
 1989(Vol:35)
 1988(Vol:34)
 1987(Vol:33)
 1986(Vol:32)