Voprosy meditsinskoi khimii (ISSN 0042-8809)

An analysis of blood serum proteins in chronic alcoholism patients by a cross immunoelectrophoresis method

   
Trubitsyna N.V., Mikheev A.M., Berezin V.A., Efimov O.E., Privalova L.I.
PubMed Id: 2773378
Year: 1989 vol: 35  issue:3  pages: 133-136
Abstract: Prealbumin, albumin, alpha 1-antitrypsin, alpha 1-antichymotrypsin, ceruloplasmin, haptoglobin, transferrin, IgG, IgM and IgA were studied in blood serum of healthy donors and of patients with chronic alcoholism by means of cross immuno-electrophoresis and immunodiffusion. Only content of alpha 1-antitrypsin was distinctly altered in blood serum of the patients with alcoholism as compared with normal state, while individual variations in content of the proteins studied were considerably higher in blood serum of the patients. At the same time, distinct dissimilarity of the patterns studied was found between healthy donors and patients with chronic alcoholism when concentration ratios of some positively and negatively charged acute phase proteins were calculated (alpha 1-antitrypsin/albumin, haptoglobin/albumin, haptoglobin/transferrin).
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Reference: Trubitsyna N.V., Mikheev A.M., Berezin V.A., Efimov O.E., Privalova L.I., An analysis of blood serum proteins in chronic alcoholism patients by a cross immunoelectrophoresis method, Voprosy meditsinskoi khimii, 1989, vol: 35(3), 133-136.
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