Voprosy meditsinskoi khimii (ISSN 0042-8809)

Characteristics of the acidic extract from the epiphysis and its fractions

   
Prokopenko N.P., Tigranian R.A., Muratova G.L., Plokhoĭ V.I., Khavinson V.Kh.
PubMed Id: 2815684
Year: 1989 vol: 35  issue:4  pages: 79-81
Abstract: Acid extract of bovine epiphyses was separated by means of gel filtration on Sephadex G-50 into two fractions: high and low molecular preparations. Estimation of biological activity of the acid extract and its polypeptide fractions, which was carried out using the procedure of antigonadotropic effect on preadolescent rat females, showed that the antigonadotropic effect was distinctly higher in the preparation free of high molecular substances.
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Reference: Prokopenko N.P., Tigranian R.A., Muratova G.L., Plokhoĭ V.I., Khavinson V.Kh., Characteristics of the acidic extract from the epiphysis and its fractions, Voprosy meditsinskoi khimii, 1989, vol: 35(4), 79-81.
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