Voprosy meditsinskoi khimii (ISSN 0042-8809)

Structural-functional properties of erythrocyte membranes in patients with infectious-allergic bronchial asthma

   
Borodin E.A., Landyshev Iu.S., Savel'eva M.V.
PubMed Id: 2534246
Year: 1989 vol: 35  issue:6  pages: 109-114
Abstract: A decrease in activity of Ca2(+)-ATPase and activation of Na+, K(+)-ATPase, correlating with elevation in content of phosphatidyl inositol and phosphatidyl serine, were detected in erythrocyte membranes of patients with the infectional-allergic form of bronchial asthma. Microviscosity of the erythrocyte membranes, estimated by fluorescence spectra of pyrene, was not altered, while negative charge as shown by ANS- fluorescence, was slightly increased on the membrane surface. Euphylline, intal, levamizole and glucocorticosteroid were found to regulate the ATPases activity in vivo and in vitro.
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Reference: Borodin E.A., Landyshev Iu.S., Savel'eva M.V., Structural-functional properties of erythrocyte membranes in patients with infectious-allergic bronchial asthma, Voprosy meditsinskoi khimii, 1989, vol: 35(6), 109-114.
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