Voprosy meditsinskoi khimii (ISSN 0042-8809)

Na,K-ATPase activity as one of criteria in identifying the risk group for development of late toxemia in pregnancy screening

   
Gun'ko S.V., Leus N.F.
PubMed Id: 2560866
Year: 1989 vol: 35  issue:6  pages: 114-117
Abstract: Activity of erythrocyte Na+, K(+)-ATPase was studied in screening of pregnant women. Alterations in total antiradical status were estimated by means of estimation of erythrocytes resistance to peroxidation. 259 healthy women with pregnancy of 20-34 weeks, without any clinical manifestations of gestosis were examined. The enzymatic activity studied was decreased in erythrocytes of women both with nonimpaired and aggravated obstetric history; these groups of women were impaired with gestosis. Functions of Na+,K(+)-Atpase enzymatic system appear to be impaired during the preclinical steps of gestosis development. Alterations in activity of Na+,K(+)-ATPase in blood of pregnant women should be used in evaluation of risk groups for development of late toxicoses.
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Reference: Gun'ko S.V., Leus N.F., Na,K-ATPase activity as one of criteria in identifying the risk group for development of late toxemia in pregnancy screening, Voprosy meditsinskoi khimii, 1989, vol: 35(6), 114-117.
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