Voprosy meditsinskoi khimii (ISSN 0042-8809)

Energy metabolism in the brain during experimental hemorrhagic shock

   
Loginova M.P., Assur M.V., Boldina I.G.
PubMed Id: 2382420
Year: 1990 vol: 36  issue:3  pages: 20-24
Abstract: State of energy metabolism was studied in brain of rats at agonal steps caused by bleeding during severe and long-term hypotension (30 mmHg, up to 30 hrs). Fast loss of high energy-containing phosphates, cell energy potential of adenine nucleotides and an increase in the lactate/pyruvate ratio were found in non-resistant rats. At the same time, in the most resistant rats normal content of creatine phosphate, ATP was maintained; energy potential was unaltered and anaerobic glycolysis was not activated. Content of glucose and glycogen did not alter considerably in all the animals studied.
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Reference: Loginova M.P., Assur M.V., Boldina I.G., Energy metabolism in the brain during experimental hemorrhagic shock, Voprosy meditsinskoi khimii, 1990, vol: 36(3), 20-24.
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