Voprosy meditsinskoi khimii (ISSN 0042-8809)

Proteolytic activity of lysosomes in various rat organs during total parenteral nutrition

   
Vasil'ev A.V., Bregvadze N.S., Poriadkov L.F., Tutel'ian V.A.
PubMed Id: 2122592
Year: 1990 vol: 36  issue:4  pages: 51-53
Abstract: Specific, total and nonsedimented activities of cathepsins A, B, C and D as well as of aryl sulfatases A and B, beta-galactosidase, beta-glucuronidase and N-acetyl-beta-D-glucosaminidase were studied in liver, kidney and spleen tissues of rats under conditions of artificial intragastric and parenteral nutrition. Activity of cathepsins A and D in liver tissue as well as total activity of all the lysosomal hydrolases studied in spleen was distinctly increased in parenteral nutrition. These data suggest elevation in the functional activity of lysosomal apparatus under conditions of parenteral nutrition.
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Reference: Vasil'ev A.V., Bregvadze N.S., Poriadkov L.F., Tutel'ian V.A., Proteolytic activity of lysosomes in various rat organs during total parenteral nutrition, Voprosy meditsinskoi khimii, 1990, vol: 36(4), 51-53.
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