Voprosy meditsinskoi khimii (ISSN 0042-8809)

Vitamin B6 level in the cerebrospinal fluid and plasma of children with acute leukemia

   
Chuvykin M.B., Shestakov V.L.
PubMed Id: 2238535
Year: 1990 vol: 36  issue:4  pages: 69-71
Abstract: Content of pyridoxal in cerebrospinal fluid exceeded its level in blood plasma of healthy children. Transport of pyridoxal through hematoencephalic barrier was decreased in children with acute leukosis, especially, with neuroleukosis, while content of pyridoxal-5-phosphate was similar to normal values. Possible mechanisms are considered which are involved in stabilization of pyroxal-5-phosphate content in cerebrospinal fluid of patients with acute leukosis, when transport of pyridoxal was impaired in central nervous system.
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Reference: Chuvykin M.B., Shestakov V.L., Vitamin B6 level in the cerebrospinal fluid and plasma of children with acute leukemia, Voprosy meditsinskoi khimii, 1990, vol: 36(4), 69-71.
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