Voprosy meditsinskoi khimii (ISSN 0042-8809)

Antioxidative properties of glycyrrhyzic acid salts and their effect on the liver monooxygenase system

   
Abdugafurova M.A., Li V.S., Sherstnev M.P., Atanaev T.B., Isamukhamedov A.Sh., Bachmanova G.I.
PubMed Id: 2251786
Year: 1990 vol: 36  issue:5  pages: 29-31
Abstract: Antioxidative activity of potassium- and sodium glycyrrhizins was detected by means of chemoluminescence procedure. As shown by the spectral studies the glycyrrhizin salts formed complex of the I type with cytochrome P-450 from rat liver microsomes, inhibited inactivation of isolated cytochrome P-450LM2 and induced hemoprotein formation after administration into rats. The preparations of glycyrrhizic acid appear to be useful for treatment of toxic impairment of liver tissue.
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Reference: Abdugafurova M.A., Li V.S., Sherstnev M.P., Atanaev T.B., Isamukhamedov A.Sh., Bachmanova G.I., Antioxidative properties of glycyrrhyzic acid salts and their effect on the liver monooxygenase system, Voprosy meditsinskoi khimii, 1990, vol: 36(5), 29-31.
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