Voprosy meditsinskoi khimii (ISSN 0042-8809)

Hetero-oligoproteins containing pancreatic ribonuclease--enzyme conjugates of prolonged action

   
Goriacheva L.K., Medvedev M.L., Samsonov G.V., Ponomareva R.B.
PubMed Id: 2251790
Year: 1990 vol: 36  issue:5  pages: 4-6
Abstract: Conjugates containing blood serum albumin and pancreatic ribonuclease, produced by means of polycondensation reaction, exhibited higher half-life in rabbit circulation as compared with non-modified enzyme. Presence of the protein-carrier contributed to elevation of the ribonuclease therapeutic efficiency and enabled to decrease the quantity of injections.
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Reference: Goriacheva L.K., Medvedev M.L., Samsonov G.V., Ponomareva R.B., Hetero-oligoproteins containing pancreatic ribonuclease--enzyme conjugates of prolonged action, Voprosy meditsinskoi khimii, 1990, vol: 36(5), 4-6.
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