Voprosy meditsinskoi khimii (ISSN 0042-8809)

Changes in the lipid composition of mitochondrial membranes during succinate oxidase reaction

   
Kapitanov A.B., Gribanov G.A., Askarova E.A., Bondareva E.V., Kulakova S.N.
PubMed Id: 2251795
Year: 1990 vol: 36  issue:5  pages: 56-58
Abstract: Content of lipids, free cholesterol, cholesterol esters, phospholipids and fatty acid composition were studied in mitochondria incubated in samples containing succinate. Induction of lipid peroxidation, production of malonic dialdehyde and alterations in membranes fluidity were not detected in the preparations of mitochondria within 3 hrs of succinate oxidation. Self-inactivation of mitochondria appears to occur due to an increased uncoupling of oxidative phosphorylation.
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Reference: Kapitanov A.B., Gribanov G.A., Askarova E.A., Bondareva E.V., Kulakova S.N., Changes in the lipid composition of mitochondrial membranes during succinate oxidase reaction, Voprosy meditsinskoi khimii, 1990, vol: 36(5), 56-58.
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