Voprosy meditsinskoi khimii (ISSN 0042-8809)

Glycosaminoglycans in leukocytes of children with bronchial asthma

   
Gerasimov A.A., Balabolkin I.I., Bakanov M.I.
PubMed Id: 2251799
Year: 1990 vol: 36  issue:5  pages: 71-75
Abstract: Content of hexuronic acids, hexoses and hexosamines was studied in lymphocytes and polymorphonuclear leukocytes of 56 children with bronchial asthma. The disease step-dependent alterations of the patterns studied were detected. Treatment of these children with bronchospasmolytic drug clenbuterol and with immunomodulator taktivine affected positively the bronchial asthma attack, which was followed by specific alterations in the carbohydrates content. Structural modifications of glycosaminoglycans in lymphocytes and phagocytes appear to be of importance for formation and development of allergic reactions in children with bronchial asthma.
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Reference: Gerasimov A.A., Balabolkin I.I., Bakanov M.I., Glycosaminoglycans in leukocytes of children with bronchial asthma, Voprosy meditsinskoi khimii, 1990, vol: 36(5), 71-75.
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