Voprosy meditsinskoi khimii (ISSN 0042-8809)

Role of lipid peroxidation in pathogenesis of visceral ischemic shock

   
Shneĭvaĭs V.B., Amilov K.S.
PubMed Id: 1949680
Year: 1991 vol: 37  issue:3  pages: 33-35
Abstract: Patterns of lipid peroxidation, chemoluminescence and antiradical activity of rat blood serum were studied after simulation of visceral-ischemic shock developed as a result of two-hour-long ischemia of the small intestines and of right-side part of large intestine. Toxic effects of oxygen, accompanied by considerable activation of lipid peroxidation, were of importance in pathogenesis of this shock. Accumulation of lipid peroxidation products in blood occurred at the step of the intestine ischemia and was distinctly increased after restoration of circulation in the tissue. Increased inhibition of blood serum chemoluminescence as well as elevation of lipid antiradical activity were observed depending on steps of the shock development.
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Reference: Shneĭvaĭs V.B., Amilov K.S., Role of lipid peroxidation in pathogenesis of visceral ischemic shock, Voprosy meditsinskoi khimii, 1991, vol: 37(3), 33-35.
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