Voprosy meditsinskoi khimii (ISSN 0042-8809)

Rat liver mitochondrial DNA treated with 1,2-dimethylhydrazine

   
Fedorov S.N., Balanski R.M., Novikov L.B., Levanova G.I., Likhachev A.Ya., Anisimov V.N., Khanson K.P.
PubMed Id: 1812622
Year: 1991 vol: 37  issue:6  pages: 82-84
Abstract: Primary structure of 5'-end 16S RNA gene of mitochondrial DNA (mDNA) isolated from rat liver tissue within 20 hrs after treatment with 1,2-dimethyl hydrazine, was analyzed. The preparations studied did not contain mutations induced by the drug. The region of mDNA analyzed appears not to be a preferential target for mutagenic effect of 1,2-dimethyl hydrazine unber these experimental conditions.
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Reference: Fedorov S.N., Balanski R.M., Novikov L.B., Levanova G.I., Likhachev A.Ya., Anisimov V.N., Khanson K.P., Rat liver mitochondrial DNA treated with 1,2-dimethylhydrazine, Voprosy meditsinskoi khimii, 1991, vol: 37(6), 82-84.
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