Voprosy meditsinskoi khimii (ISSN 0042-8809)

Glycosaminoglycans in syrinogomyelia

Elaev N.R., Safin Sh.M., Borisova N.A., Kamilov F.Kh.
PubMed Id: 1441283
Year: 1992 vol: 38  issue:1  pages: 13-15
Abstract: Excretion of glycosaminoglycans (GAG) with urine was 2.7-fold decreased in patients with syringomyelia as compared with healthy persons. Patterns of GAG decreased excretion are genetically determined and inherited as dominant features. Content of GAG was decreased in the patients skin, cerebrospinal fluid and brain by 30%, 40% and 20-40%, respectively; content of GAG was increased by 80% in spinal cord where the pathological process was localized. The data obtained suggest that considerable impairment of connective tissue metabolism occurred in syringomyelia.
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Reference: Elaev N.R., Safin Sh.M., Borisova N.A., Kamilov F.Kh., Glycosaminoglycans in syrinogomyelia, Voprosy meditsinskoi khimii, 1992, vol: 38(1), 13-15.