Voprosy meditsinskoi khimii (ISSN 0042-8809)

Proteolytic mechanisms in bronchial secretions in rats with bronchial anaphylaxis

   
Komov V.P., Spasenkova O.M., Strelkova M.A.
PubMed Id: 1441285
Year: 1992 vol: 38  issue:1  pages: 18-20
Abstract: Serine elastase-like proteinase was isolated from rat bronchial secretion, activity of which was increased 2-fold in bronchial anaphylaxis. Effect of histamine, serotonin and hydrocortisone on the enzymatic activity was studied. Regulation of the enzyme activity in bronchial anaphylaxis was considered with relation to patterns of its metabolism as well as depending on efficiency of specific endogenous inhibitor of the proteinase. A procedure for histamine stimulation of alkaline proteinase was developed.
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Reference: Komov V.P., Spasenkova O.M., Strelkova M.A., Proteolytic mechanisms in bronchial secretions in rats with bronchial anaphylaxis, Voprosy meditsinskoi khimii, 1992, vol: 38(1), 18-20.
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