Voprosy meditsinskoi khimii (ISSN 0042-8809)

Effect of biogenic amines on glycogen degradation in isolated rat hepatocytes

   
Popova I.A., Presnova V.N., Lavrenova T.P.
PubMed Id: 1413626
Year: 1992 vol: 38  issue:2  pages: 30-33
Abstract: Serotonin and tyramine affected dissimilarly the enzyme activity involved in degradation of glycogen in isolated rat hepatocytes. Serotonin inhibited hydrolytic enzymes acid alpha-glucosidase, alpha-amylase and amylo-1,6-glucosidase but activated phosphorylase inducing a decrease of glycogen content in cells. Tyramine inhibited acid alpha-glucosidase and amylo-1,6-glucosidase, did not affect the alpha-amylase and phosphorylase activities and increased content of glycogen in cells. Tyramine may be used as stimulator of glycogen accumulation in liver cells.
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Reference: Popova I.A., Presnova V.N., Lavrenova T.P., Effect of biogenic amines on glycogen degradation in isolated rat hepatocytes, Voprosy meditsinskoi khimii, 1992, vol: 38(2), 30-33.
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