Voprosy meditsinskoi khimii (ISSN 0042-8809)

Assessment of vitamin B2, B6, and PP supply from data on excretion of vitamins and their metabolites in alimentary iron and riboflavin deficiency

   
Alekseeva I.A., Kodentsova V.M., Vrzhesinskaia O.A., Zvereva T.E., Khotimchenko S.A., Spirichev V.B.
PubMed Id: 1492387
Year: 1992 vol: 38  issue:5  pages: 17-20
Abstract: Alimentary deficiency in riboflavin and/or iron in rats involved distinct decrease in excretion of 4-pyridoxylic acid and 1-N-methyl nicotinamide--the metabolites considered as the indices of vitamins B6 and PP consumption. The effect observed appears to occur due to a decrease in activity of some iron- and flavin-containing enzymes participating in the metabolism of pyridoxine and niacin. Addition to the diet of the deficient component normalized these patterns. Use of the data on excretion of 4-pyridoxylic acid and 1-N-methyl nicotinamide as criteria of consumption of pyridoxine and niacin is discussed.
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Reference: Alekseeva I.A., Kodentsova V.M., Vrzhesinskaia O.A., Zvereva T.E., Khotimchenko S.A., Spirichev V.B., Assessment of vitamin B2, B6, and PP supply from data on excretion of vitamins and their metabolites in alimentary iron and riboflavin deficiency, Voprosy meditsinskoi khimii, 1992, vol: 38(5), 17-20.
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