Voprosy meditsinskoi khimii (ISSN 0042-8809)

Carbohydrate metabolism upon disruption of monoaminergic regulatory mechanisms, developing in the early post-resuscitation period

   
Lobov V.V., Konvaĭ V.D., Bykhovtsev A.N.
PubMed Id: 1337228
Year: 1992 vol: 38  issue:5  pages: 26-28
Abstract: Within the early period after clinical death of various duration, hyperglycemia developed in dogs as a result of increased secretion of catecholamines; the rate of hyperglycemia depended on the severity of postresuscitation impairments of the central nervous system. Content of blood glucose was increased simultaneously with elevation of insulin production. Within 1-2 hrs after administration of dihydroxyphenylalanine the excessive secretion of catecholamines altered adrenoreceptor system sensitivity in Langerhans islands with the subsequent decrease in insulin production. Content of cAMP in brain of resuscitated dogs as compared with controls was increased less drastically.
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Reference: Lobov V.V., Konvaĭ V.D., Bykhovtsev A.N., Carbohydrate metabolism upon disruption of monoaminergic regulatory mechanisms, developing in the early post-resuscitation period, Voprosy meditsinskoi khimii, 1992, vol: 38(5), 26-28.
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