Voprosy meditsinskoi khimii (ISSN 0042-8809)

Brain monoamine oxidase in aging wild Norway rats, chosen for lack of aggressive behavior toward humans

   
Voĭtenko N.N.
PubMed Id: 8511882
Year: 1993 vol: 39  issue:2  pages: 28-30
Abstract: Monoamine oxidase A and B (MAO A; MAO B) activity was studied in the brain stem and hemispheres of young (4 months) and old (7 months) wild Norway rats of S35-S36 bred for absence of aggressive reactions to men (tame), bred for pronounced aggressive reaction for the same number of generations (aggressive), and those not undergoing any breeding (wild). In young tame rats MAO B activity was lower than in wild ones of the same age. As the animals grew older, in 7 months, MAO B activity increased in the brain stem and hemispheres of all the rats, irrespectively of the type of behavior. Difference in MAO B activity found between tame and wild 4-month rats disappeared at the age of 7 months. MAO A activity did not change either with ageing or due to breeding for behavior.
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Reference: Voĭtenko N.N., Brain monoamine oxidase in aging wild Norway rats, chosen for lack of aggressive behavior toward humans, Voprosy meditsinskoi khimii, 1993, vol: 39(2), 28-30.
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