Voprosy meditsinskoi khimii (ISSN 0042-8809)

Features of autolytic restructuring of lipids in plasma, serum, and blood clots

Gribanov G.A., Lutskaia N.V.
PubMed Id: 8333177
Year: 1993 vol: 39  issue:3  pages: 12-14
Abstract: Quantitative composition and amount of main lipid fractions were studied by means of microthin-layer chromatography in blood clot free of cell elements, in blood serum and plasma obtained from volunteers as well as their alterations were estimated in dynamics of autolysis. Dissimilar alterations were detected in total lipids and their individual fractions in the preparations studied. Under conditions of incubation the lipid component was found to be highly labile in blood plasma and serum, where total content of lipids was distinctly decreased, while the lipids content was not considerably altered in blood clot. Content of phospholipids was most distinctly decreased with simultaneous accumulation of free fatty acids in all the preparations studied. The most considerable transformations were observed within early steps of autolysis. Dissimilar composition and activity of the enzymatic systems involved in biodegradation and biotransformation of lipid components as well as specific metabolic relations between lipids may be responsible for these differences in the type and rate of autolytic transformations of lipid components in blood plasma, serum and clot.
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Reference: Gribanov G.A., Lutskaia N.V., Features of autolytic restructuring of lipids in plasma, serum, and blood clots, Voprosy meditsinskoi khimii, 1993, vol: 39(3), 12-14.