Voprosy meditsinskoi khimii (ISSN 0042-8809)

Correlation of lipid peroxidation intensity and insulin reception in adipocytes

   
Ivanov V.V., Stennikova M.P.
PubMed Id: 8379107
Year: 1993 vol: 39  issue:4  pages: 23-25
Abstract: Influence of prooxidants (cumene hydroperoxide and Fe2+) on insulin reception by adipocytes was studied in experimental conditions. Cumene hydroperoxide (10(-7) M) in the presence of Fe2+ (0.2 mM) increased the specific binding of the hormone. The higher concentrations (10(-6)-10(-3) M) of the prooxidant resulted in significant accumulation of malonic dialdehyde and inhibited insulin binding by fat tissue cells. The inhibition of insulin specific binding was shown to occur due to a decrease in the content of insulin receptors as well as in the rate of their affinity to the hormone.
Download PDF:
Reference: Ivanov V.V., Stennikova M.P., Correlation of lipid peroxidation intensity and insulin reception in adipocytes, Voprosy meditsinskoi khimii, 1993, vol: 39(4), 23-25.
References
 1995(Vol:41)
 1994(Vol:40)
 1993(Vol:39)
 1992(Vol:38)
 1991(Vol:37)
 1990(Vol:36)
 1989(Vol:35)
 1988(Vol:34)
 1987(Vol:33)
 1986(Vol:32)