Cellular mechanisms of calcium regulation of cardiac rhythm in children with ectopic arrhythmias | 
 
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| Bershova T.V., Bakanov M.I., Bokeriia L.A., Serbin V.I., Mamedova T.N., Mikhaĭlova I.L. | | PubMed Id: 7526547 | | Year: 1994 vol: 40 issue:4
pages: 50-53 | | Abstract: Regulation of intracellular calcium homeostasis by means of secondary mediators calmodulin and 4,5-inositol phosphates (products of phosphatidyl inositol hydrolysis) was studied in children with ectopic forms of arrhythmias. Alterations in the system calmodulin-Ca2+ and the activity of phosphoinosite metabolism correlated highly with clinical manifestations of the arrhythmias. The data obtained suggest that a number of molecular mechanisms and responsible for arrhythmias were realized in cell membranes and depended on a complex of intracellular messengers affected within various steps of the hormonal signal transmission. | | Download PDF: | | Reference: Bershova T.V., Bakanov M.I., Bokeriia L.A., Serbin V.I., Mamedova T.N., Mikhaĭlova I.L., Cellular mechanisms of calcium regulation of cardiac rhythm in children with ectopic arrhythmias, Voprosy meditsinskoi khimii, 1994, vol:
40(4), 50-53. | |
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