Voprosy meditsinskoi khimii (ISSN 0042-8809)

Metabolism of the basic component of connective tissue at various stages of developing experimental liver cirrhosis

   
Skobeleva T.V.
PubMed Id: 7839660
Year: 1994 vol: 40  issue:5  pages: 17-20
Abstract: A system of GAG-hydrolase was studied in liver tissue and blood plasma during development of CCl4-produced cirrhosis of liver tissue in series of experiments involving 400 adult rat males. Dissimilar pathways of the matrix formation, related to dynamics of the GAG-hydrolases activity, were detected within various steps of the chronic CCL4-produced liver tissue impairments in these rats. Alterations in the enzymatic activity were stable and regular in each series of the experiment and correlated with dynamics of the adaptation-compensatory responses
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Reference: Skobeleva T.V., Metabolism of the basic component of connective tissue at various stages of developing experimental liver cirrhosis, Voprosy meditsinskoi khimii, 1994, vol: 40(5), 17-20.
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