Voprosy meditsinskoi khimii (ISSN 0042-8809)

Changes in blood concentration of thyroid hormones after subtotal thyroidectomy, external or internal radiation

   
Shkuratov L.M., Krylova I.M., Markova A.G., Bagel I.M.
Type: Experimental study
PubMed Id: 9148592
Year: 1996 vol: 42  issue:2  pages: 111-114
Abstract: Thyroidectomy or administration of high activities (> 1.1 Mbq) of 131I to rats causes initial decrease in blood concentration of thyroid hormones which returns to the normal level. Administration of lower doses (< 1.1 Mbq) of radioactive iodine or external radiation (1, 3, 6 Gr) did not cause similar changes. Data obtained that: 1) thyroid gland is relatively radioresistant organ with high reparative function after surgical or radioactive damage; 2) alterations of thyroid status after the external radiation are not related to a direct action of radiation on the thyroid gland.
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Reference: Shkuratov L.M., Krylova I.M., Markova A.G., Bagel I.M., Changes in blood concentration of thyroid hormones after subtotal thyroidectomy, external or internal radiation, Voprosy meditsinskoi khimii, 1996, vol: 42(2), 111-114.
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