Voprosy meditsinskoi khimii (ISSN 0042-8809)

Experimental study of formaldehyde action on the enzyme activity of rat liver during ontogenesis

   
Astakhova L.F., Mukhambetova L.H., Koganova Z.I., Dolinskaya S.I., Kazachkov V.I., Zhurkov V.S.
Type: Experimental study
PubMed Id: 9139453
Year: 1996 vol: 42  issue:3  pages: 217-222
Abstract: The pregnant rats were treated with formaldehyde (0.5 mg/kg daily per os) during whole period of pregnancy. The activity of cytochrome-c-oxidase, malate dehydrogenase, nucleotidase, glucose-6-phosphatase, beta-glucuronidase, N-acetyl-beta-glucosaminidase, beta-galactosidase, H(+)-ATPase, glutamate dehydrogenase, NAD- and NADP-isocitrate dehydrogenase, fructose-bisphosphate aldolase, glucose-6-phosphate dehydrogenase and content of protein in liver celts of offsprings (newborns, 2 weeks age and 2 months age) were studied. It was shown differences in development enzyme systems of control and experimental animals during ontogenesis.
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Reference: Astakhova L.F., Mukhambetova L.H., Koganova Z.I., Dolinskaya S.I., Kazachkov V.I., Zhurkov V.S., Experimental study of formaldehyde action on the enzyme activity of rat liver during ontogenesis, Voprosy meditsinskoi khimii, 1996, vol: 42(3), 217-222.
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