Voprosy meditsinskoi khimii (ISSN 0042-8809)

The influence of lead on the metabolism of vitamin B group at the alimentary iron deficit in rats

   
Khotimchenko S.A., Kodentsova V.M., Alekseeva I.A., Vlaskina S.G., Vrzhesinskaya O.A., Kharitonchik L.A., Aleshko-Azhevskiy Yu.P., Shevyakova L.V., Sokolnikov A.A.
PubMed Id: 9273779
Year: 1997 vol: 43  issue:3  pages: 158-164
Abstract: Experimentally induced lead poisoning especially under simultaneous iron deficit leads to the development of secondary thiamine insufficiency. Erythrocyte riboflavin content and erythrocyte glutathion reductase and aspartate aminotransferase activities have been demonstrated to be increased. Lead treatment is accompanied with the increase of urinary excretion of riboflavin, 4-pyridoxic acid and 1-vtthylnicotinamide in rats fed with adequate diet. Thus lead intoxication and iron deficiency influence vitamin B group metabolism.
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Reference: Khotimchenko S.A., Kodentsova V.M., Alekseeva I.A., Vlaskina S.G., Vrzhesinskaya O.A., Kharitonchik L.A., Aleshko-Azhevskiy Yu.P., Shevyakova L.V., Sokolnikov A.A., The influence of lead on the metabolism of vitamin B group at the alimentary iron deficit in rats, Voprosy meditsinskoi khimii, 1997, vol: 43(3), 158-164.
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