Voprosy meditsinskoi khimii (ISSN 0042-8809)

Application of the chemiluminescent assay for the investigation of free radical lipid peroxidation in rat brain after the cranio-cerebral trauma

   
Promyslov M. Sh., Demchuk M. L., Poryadina L. V., Voronov V. G.
PubMed Id: 9312934
Year: 1997 vol: 43  issue:4  pages: 208-211
Abstract: The method of chemiluminescence was applied for the determination of free radicals content in rabbit brain after the experimental craniocerebral trauma. The level of malone dialdehyde was measured spectrophotometrically. The quantity of free radical products in hemispheres, brain stem and cerebellum of rabbits with traumatic injury was shown to be significantly increased and correlated with MDA level. Data obtained indicate that the chemiluminescent technique can be useful for the investigation of lipid peroxidation in brain pathology.
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Reference: Promyslov M. Sh., Demchuk M. L., Poryadina L. V., Voronov V. G., Application of the chemiluminescent assay for the investigation of free radical lipid peroxidation in rat brain after the cranio-cerebral trauma, Voprosy meditsinskoi khimii, 1997, vol: 43(4), 208-211.
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