Voprosy meditsinskoi khimii (ISSN 0042-8809)

The influence of oral inulin administration on fructose-2, 6-diphosphate level in liver of rats with streptozotocin diabetes

   
Guseva D.A., Gorodetsky V.K., Kraevoi S.A., Markova M.S., Tsyganova T.B.
PubMed Id: 9312940
Year: 1997 vol: 43  issue:4  pages: 247-255
Abstract: The influence of oral inulin administration on glucose and fructose content in blood, glucose and ketone bodies in urine, and fructose-2,6-diphosphate content in liver was investigated in rats with streptozotocin diabetes. Short-term administration (during 5-6 days) of 0,5% inulin solution caused three-fold increase of blood fructose compared with control, normalisation of blood glucose and disappearance of glucose- and ketoneuria. The level of fructose-2,6-diphosphate in liver increased to the control level. Inulin administration during 12 days caused five-fold increase of blood fructose compares with control, glucose level increased up to the level of uncured diabetes (22 mmol/l), glucose- and ketoneuria appeared. The content of fructose-2,6-diphosphate in the liver decreased to diabetic level.
Download PDF:
Reference: Guseva D.A., Gorodetsky V.K., Kraevoi S.A., Markova M.S., Tsyganova T.B., The influence of oral inulin administration on fructose-2, 6-diphosphate level in liver of rats with streptozotocin diabetes, Voprosy meditsinskoi khimii, 1997, vol: 43(4), 247-255.
References
 2002(Vol:48)
 2001(Vol:47)
 2000(Vol:46)
 1999(Vol:45)
 1998(Vol:44)
 1997(Vol:43)
 1996(Vol:42)