Voprosy meditsinskoi khimii (ISSN 0042-8809)

The use of antisence oligonucleotides for modulation of cytokine gene expression

   
Kozlov V.A., Sennikov S.V.
PubMed Id: 9446321
Year: 1997 vol: 43  issue:5  pages: 308-320
Abstract: The review summarizes literature data on the mechanism of action and theuse of antisence oligonucleotides for modulation of cytokine gene expressionin haemo- and immunopoesis. This new approach for gene-directed modulationof the gene expression allows to analyze both intercellular and intracellularprotein interaction. Use of this approach is prospective for both experimentalresearches in vivo and in vitro and application in therapeutic purposes.
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Reference: Kozlov V.A., Sennikov S.V., The use of antisence oligonucleotides for modulation of cytokine gene expression, Voprosy meditsinskoi khimii, 1997, vol: 43(5), 308-320.
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