Voprosy meditsinskoi khimii (ISSN 0042-8809)

The role of immune inflammnation in atherogenesis

Nagornev V.A., Rabinovich V. S.
PubMed Id: 9446324
Year: 1997 vol: 43  issue:5  pages: 339-348
Abstract: Data on cellular-molecular aspects of the development of immune inflammationin vascular wall under atherogenesis are considered. Own results and literaturedata on the investigation of mechanism of adhesion of agrannulated leucocyteson endothelium, role of macrophages and T-cells in modification of apoproteinB-containing lipoproteins, production and secretion of proinflammatorycytokines and acute phage proteins by «intima» cells are considered.A conception evaluating atherogenesis as a local immune inflammation inthe arterial wall is considered.
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Reference: Nagornev V.A., Rabinovich V. S., The role of immune inflammnation in atherogenesis, Voprosy meditsinskoi khimii, 1997, vol: 43(5), 339-348.