Voprosy meditsinskoi khimii (ISSN 0042-8809)

Gene therapy of vascular diseases

Zelenin A.V.
PubMed Id: 10432554
Year: 1999 vol: 45  issue:3  pages: 200-205
Abstract: Gene therapy of vascular diseases represents a new perspective field inthe modern biomedical science. It is based on the employment of genetic constructions formedical treatment. The paper reviews major directions in gene therapy of vasculardiseases: inhibition of proliferative processes in the vascular wall; administration intothe elements of vascular wall of genes responsible for nitric oxide synthesis;normalisation of blood pressure regulatory system; synthesis of thromboembolic factors andanticoagulants; gene therapy of atherosclerosis; revascularisation of ischaemic myocardiumand inhibition of tumor vascularisation.
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Reference: Zelenin A.V., Gene therapy of vascular diseases, Voprosy meditsinskoi khimii, 1999, vol: 45(3), 200-205.