Voprosy meditsinskoi khimii (ISSN 0042-8809)

Antioxidant properties of arbidol and its structural analogues

   
Vasiljeva O.V., Lyubitsky O.B., Guskova T.A., Glushkov R.G., Medvedev O.S., Vladimirov Yu.A.
PubMed Id: 10547883
Year: 1999 vol: 45  issue:4  pages: 326-331
Abstract: The effect of arbidol and its structural analogues on the process oflipid peroxidation in phospholipid liposomes induced by Fe2+ has beeninvestigated. It was shown that the antioxidant efficacy of arbidol and its derivatives islower than that of a -tocopherol by two or three times. It wassuggested that the mechanism antioxidant action of the arbidol and its structuralanalogues consists of scavenging of lipid radicals rather than chelating of Fe2+.
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Reference: Vasiljeva O.V., Lyubitsky O.B., Guskova T.A., Glushkov R.G., Medvedev O.S., Vladimirov Yu.A., Antioxidant properties of arbidol and its structural analogues, Voprosy meditsinskoi khimii, 1999, vol: 45(4), 326-331.
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