Voprosy meditsinskoi khimii (ISSN 0042-8809)

The trypsin-like activity, elastase-like activity and antiproteinase potential in patients with contusion injury of the eye

   
Bendelic E.C., Dotsenko V.L., Neshkova E.A., Moshetova L.C., Yarovaya G.A.
PubMed Id: 10547885
Year: 1999 vol: 45  issue:4  pages: 339-345
Abstract: The investigations of tear fluid of eye after contusion injury revealedon increase of trypsin-like activity in 1-3 day and 10-19 day after trauma, theprogressivelly elevation of elastase-like activity and lowering of inhibitory potentialalong 2-3 week. It was detected indirect correlation between the elastase-like activityand severity of the contusion injury of the eye, the grade of corneal edema, cornealerosion and conjunctival wound, hyphema. This results was shown the partisipation and therole of proteolytic and inflammatory processes in pathogenisis of eye blunt trauma. It wasestablish that the during of local inflammation is 2 week end more and is necesseryantiinflammatory teraphy with use the proteases inhibitors.
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Reference: Bendelic E.C., Dotsenko V.L., Neshkova E.A., Moshetova L.C., Yarovaya G.A., The trypsin-like activity, elastase-like activity and antiproteinase potential in patients with contusion injury of the eye, Voprosy meditsinskoi khimii, 1999, vol: 45(4), 339-345.
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