Voprosy meditsinskoi khimii (ISSN 0042-8809)

Vanadium compounds as a new class of therapeutical agents for treatment of diabetes mellitus

   


1. Institute of Biomedical Chemistry, Russian Academy of Medical Sciences
PubMed Id: 11075417
Year: 2000 vol: 46  issue:4  pages: 344-360
Abstract: Vanadium compounds as insulin mimics with promising therapeuticproperties are reviewed. The biological effects of both inorganic forms of vanadium andvanadyl organic complexes are decried for various animal models. These effects includehypoglycemic and insulin reserve actions, insulin sensitivity enhance, cholesterollowering and other manifestations. The effectiveness of vanadium compounds in diabetestreatment is confirmed with clinical trials. The possible mechanisms of insulin-likeeffects of vanadium are discussed. The various nutritional supplements for patients withdiabetes mellitus including vanadium-contained used in Russia and abroad are alsoconsidered.
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Reference: Belayeva N.F., Gorodetskii V.K., Tochilkin A.I., Golubev M.A., Semenova N.V., Kovelman I.R., Vanadium compounds as a new class of therapeutical agents for treatment of diabetes mellitus, Voprosy meditsinskoi khimii, 2000, vol: 46(4), 344-360.
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