Voprosy meditsinskoi khimii (ISSN 0042-8809)

The effect ofantibiotic therapy on embryotropic antibodies in women

   


1. Municipal hospital №29 Committee for health, Moscow, Orekhovich Institute of Biomedical Chemistry RAMS
2. Fund Chernobyl-Test
3. Department of obstetrics and gynecology, Peoples Frendship University, Moscow
4. Orekhovich Institute of Biomedical Chemistry RAMS
PubMed Id: 11450447
Year: 2001 vol: 47  issue:2  pages: 256-154
Abstract: Embriotropic antibodies (e-Ab) serum contents were analysed in 29 serumsamples obtained from women suffering withprimary lues. Before treatment the content of e-Ab against MBP, S100, ACBP14/18, and MP65were markedly elevated in 28 samples. Two injections of Retarpen (2,5 mln Units with oneweek interval) were enough for effective treatment of lues.At the same time treatment caused deep and reversible inhibition of e-Ab production. One or two months later thelevels of e-Ab returned to normal values in 21% of women, in 52% patients thehypoproduction, and in 27% the hyperproduction of e-Ab were noted. Deviations of e-Abproduction after effective retarpen treatment suggest the existence of additional reasonswhich may influence e-Ab production, and necessity of additional diagnostic and curativemeasures for such women during pregravidal period.
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Reference: Morozov S.G., Poletaev A.B., Radzinsky V.Е., Protsenko A.N., Korgenevskii D.A., The effect ofantibiotic therapy on embryotropic antibodies in women, Voprosy meditsinskoi khimii, 2001, vol: 47(2), 256-154.
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