Voprosy meditsinskoi khimii (ISSN 0042-8809)

Brain monoamine oxidase in prematurely aging oxys rats


1. Institute of Cytology and Genetics, Siberian Branch of the Russian Acad.Sci.
PubMed Id: 11925747
Year: 2001 vol: 47  issue:6  pages: 582-587
Abstract: Rats OXYS with manifestations of genetically determined premature aging and OXYR freefrom these manifestation were studied.Eight month old OXYS and OXYR rats werecharacterized by similar brain stem MAO A and MAO B activities and their control at thetranscription level. In hemispheres of 8 month old OXYS rats MAO A activity was higherthan in OXYR. Emotional stress did not affect either MAO A or MAO B in brain stem of thetwo strains, and lowered MAO A activity in hemispheres of OXYS rats.
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Reference: Voitenko N.N., Brain monoamine oxidase in prematurely aging oxys rats, Voprosy meditsinskoi khimii, 2001, vol: 47(6), 582-587.