Voprosy meditsinskoi khimii (ISSN 0042-8809)

Antioxidative system of rat tissues in hypothermia and dalargin injection

   


1. Research Institute of Biology, Dagestan State University
PubMed Id: 12189626
Year: 2002 vol: 48  issue:2  pages: 189-195
Abstract: Total antioxidative activity, activity of water soluble fraction of antioxidative system, syperoxide dismutase and catalase activities in brain, liver, myocard, skeletal muscle, kidney and serum at hypothermia 300С, 200С and self-warming from 200С to 370С were studied. Activity of antioxidative system is sustained at high level, except superoxide dismutase. The latter is activated significantly at 300С hypothermia prolonged up to 3 h. Dalargin injection 30 min before onset of cooling stabilizes the erythrocyte membrane without enhancement of antioxidative activity in majority of investigated tissues
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Reference: Lvova S.P., Abaeva E.M., Gasangadzhiyeva A.G., Mikhaylenko I.K., Antioxidative system of rat tissues in hypothermia and dalargin injection, Voprosy meditsinskoi khimii, 2002, vol: 48(2), 189-195.
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