Voprosy meditsinskoi khimii (ISSN 0042-8809)

Alteration of activity ofangiotensin converting enzyme in chronicobstructive pulmonary diseases and acute pneumonia

   


1. Semashko Central clinical hospital, Russian ministry of railway
2. Russian Academy of Postgraduate Education, Moscow
3. Sechenov Moscow Medical Academy, Moscow
4. State Medical Institute for Postgraduate Training, Defense Ministry, Moscow
PubMed Id: 12189629
Year: 2002 vol: 48  issue:2  pages: 204-214
Abstract: The activity of angiotensinconverting enzyme (ACE) was analysed in blood serum and bronchial fluid of 69 patientswith acute pneumonia and 77 patients with chronic obstructive pulmonary diseases (COPD).In patients with pneumonia in acute phase ACE activity was lower in both serum andbronchial fluid. During recovery of patients with acute pneumonia ACE activity wasnormalized. In patients with COPD ACE activity was lower in remission stage andhigher (both serum and bronchial fluid) during COPD exacerbation. The changes of ACEactivity were more pronounced in bronchial fluid than serum in both COPD and pneumonia.
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Reference: Altchouler B.Y., Roitman A.P., Fedorova T.A., Yarovay G.A., Neshkova E.A., Novozhenov V.G., Belkov S.A., Alteration of activity ofangiotensin converting enzyme in chronicobstructive pulmonary diseases and acute pneumonia, Voprosy meditsinskoi khimii, 2002, vol: 48(2), 204-214.
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