Voprosy meditsinskoi khimii (ISSN 0042-8809)

Effect of UV-radiation on the level of ascorbate, sh-groups and activity of glutathione reductase in the eyelens

   


1. Byelorussion State University, Biology Faculty, Department of Biochemistry
PubMed Id: 12498087
Year: 2002 vol: 48  issue:5  pages: 455-460
Abstract: he effect of UV radiation in vitro on the level of ascorbate, SH-groups and glutathione reductase activity in the soluble fraction of bovine eye lens was studied. UV-Irradiation increased NADPH-oxidoreductase activity, the level of ascorbate oxidation and decreased the content of SH-groups and activity of glutathione reductase. Significant activation of the NADPH-oxidoreductase activity in the presence of ascorbate and Cu2+ was observed after UV-irradiation. It is suggested thаt ascorbate may play an important role in the UV-induced lens pathology
Download PDF:
Reference: Byshneva L.N., Senchuk V.V., Effect of UV-radiation on the level of ascorbate, sh-groups and activity of glutathione reductase in the eyelens, Voprosy meditsinskoi khimii, 2002, vol: 48(5), 455-460.
References
 2002(Vol:48)
 2001(Vol:47)
 2000(Vol:46)
 1999(Vol:45)
 1998(Vol:44)
 1997(Vol:43)
 1996(Vol:42)