Voprosy meditsinskoi khimii (ISSN 0042-8809)

Influence of GABA and pyracetam on mitochondrial adpphosphorylation system in conditions of experimental hypokinesia

   


1. Department of Pharmacology, Yerevan State Medical University
PubMed Id: 12498091
Year: 2002 vol: 48  issue:5  pages: 485-489
Abstract: Long-term limitation of motoractivity of male rats is accompanied by impairments of mitochondrial ADP phosphorylationin liver and heart. The most significant changes were observed after 15 and 45 days ofhypokinesia. Administration of GABA and pyracetam to animals subjected to hypokinesiainduced a tendency to "normalization" of ADP phosphorilation processes.
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Reference: Sotckiy O.P., Hakopyan V.P., Jamgaryan L.G., Jamgaryan A.G., Influence of GABA and pyracetam on mitochondrial adpphosphorylation system in conditions of experimental hypokinesia, Voprosy meditsinskoi khimii, 2002, vol: 48(5), 485-489.
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