Voprosy meditsinskoi khimii (ISSN 0042-8809)

Changes in system of antioxidant blood defence in newborns with different pathology

   


1. Saint-Petersburg Pediatric Medical Academy
PubMed Id: 12498095
Year: 2002 vol: 48  issue:5  pages: 513-518
Abstract: Blood antioxidant enzymes (superoxide dismutase, catalase, ceruloplasmin) were investigated in gestational ages and diseases. Low activity of blood superoxide dismutase and catalase were observed in premature babies and in newborns after acute and chronic hypoxia. In hemolytic disease the aсtivity of antioxidant enzymes of newborns was significantly higher than in healthy infants. This work demonstrates advantages of haemosorbtion compared to exchange blood transfusion. So the antioxidant activity in blood, decreased after blood transfusion, remained at a high level after haemosorbtion. Аny deficiency of antioxidant enzymes in newborns may lead to toxyc oxygen effects. Antioxidants are potential therapeutic agents in the above mentioned conditions
Download PDF:
Reference: Litvinenco L.A., Danilova L.A., Shabalov N.P., Changes in system of antioxidant blood defence in newborns with different pathology, Voprosy meditsinskoi khimii, 2002, vol: 48(5), 513-518.
References
 2002(Vol:48)
 2001(Vol:47)
 2000(Vol:46)
 1999(Vol:45)
 1998(Vol:44)
 1997(Vol:43)
 1996(Vol:42)