Voprosy meditsinskoi khimii (ISSN 0042-8809)

Isolation, purification, and properties of factor XII and its active fragment (beta-XIIa)

   


1. Russian Medical Academy of Postgraduate Education
PubMed Id: 12698561
Year: 2002 vol: 48  issue:6  pages: 603-610
Abstract: A procedure of isolation of human blood plasma prekallikrein, coagulation factor XII and active fragment beta-XIIa has been developed. This procedure includes the traditional chromatography steps and FPLC. Disc-electrophoresis revealed that the preparations of factor XII and beta-XIIa were homogeneous. Their specific activity was 70.6 U and 2.5 U, respectively. The procedure described is less time consuming and it allows to isolate these factors in the preparative quantities.
Download PDF:
Reference: Blokhina T.B., Neshkova E.A., Yarovaya G.A., Isolation, purification, and properties of factor XII and its active fragment (beta-XIIa), Voprosy meditsinskoi khimii, 2002, vol: 48(6), 603-610.
References
 2002(Vol:48)
 2001(Vol:47)
 2000(Vol:46)
 1999(Vol:45)
 1998(Vol:44)
 1997(Vol:43)
 1996(Vol:42)