Biological effects of flaxseed oil as the source of alpha -linolenic acid omega-3


1. Orehovich Institute of Biomedical Chemistry Russian Academy of Medical Sciences
2. Moscow State Technological Academy
Type: Review
PubMed Id: 15108624
Year: 2004 vol: 50  issue:1  pages: 25-43
Abstract: Flaxseed oil is the most abundant plant source of omega-3 fatty acid, a-linolenic acid omega-3. This review focuses on the biological effects of dietary a-linolenic acid (ALA) compared with long-chain w-3 derivatives. ALA is not equivalent in its biological effects to the long-chain w-3 fatty acids found in marine fish oils. However, ALA is metabolized to eicosapentaenoic acid, which may replace arachidonic acid in membrane phospholipides. Ingestion of flaxseed oil may alter the generation of eicosanoids, procoagulant activity and other membrane-dependent responses and exert antiallergic, antiatherosclerotic, antiarrhythmic effects. Beneficial еffects of flaxseed oil have been shown in prevention and management of cardiovascular disease.
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Reference: Ipatova O.M., Prosorovskaya N.N., Baranova V.S., Guseva D.A., Biological effects of flaxseed oil as the source of alpha -linolenic acid omega-3, Biomeditsinskaya khimiya, 2004, vol: 50(1), 25-43.