Abstract: The effect of Arochlor 1254 treatment of rats on activities of cytochrome P450 isoforms 1A1, 1A2, 2C6 was investigated under conditions of acute pancreatitis. Irrespectively to the scheme of Arochlor 1254 administration (before the development of pancreatitis, and at various periods after its provocation) cytochrome P450 activities were higher than in corresponding controls.
Reference: Prokopieva N.V., Gulyaeva L.F., Polyakova N.E., Changes of hepatic microsomal monooxygenase system during acute pancreatitis and arochrolor 1254 induction on rats, Biomeditsinskaya khimiya, 2004, vol:
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