Contents of neuromediatory amino acids in human blood plasma during Parkinson's disease

   


1. Institute of Neurology, Russian Academy of Medical Sciences
Type: Experimental/clinical study
PubMed Id: 15108632
Year: 2004 vol: 50  issue:1  pages: 92-99
Abstract: Content of neurotransmitter amino acids before and after treatment with Не-Ne-laser was measured in blood of two groups of the Parkinson's disease patients distinguished by low (first group) and high (second group) activity of monoamine oxidase B and Cu/Zn-superoxide dismutase. An increase in taurine level at the early stage of the disease (first group of patients) suggests taurine may by a marker of compensatory abilities of the organism. The violation of the glutamate/taurine that balance at the later stages of the disease and its normalization following the laserotherapy accompanied with improvement of neurological symptoms.
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Reference: Vitreshchak T.V., Poleshchuk V.V., Piradov M.A., Contents of neuromediatory amino acids in human blood plasma during Parkinson's disease, Biomeditsinskaya khimiya, 2004, vol: 50(1), 92-99.
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